Most antifreeze solutions contain high levels of ethylene glycol, an ingredient that, once metabolized, is extremely toxic to dogs and cats. Pets are often attracted to the liquid because of its sweet taste. Even small amounts can be lethal to animals. A cat that walks through spilled antifreeze and then licks its paws may ingest enough to be fatal. As little as 2.5 tablespoons of antifreeze could kill a 20-pound dog.