Glucocorticoids (primarily cortisol) and mineralocorticoids are two important types of hormones produced by the body’s adrenal glands. Under normal conditions, the brain releases a hormone called adrenocorticotropic hormone (ACTH) that stimulates the adrenal glands to release their hormones. Addison’s disease occurs when the brain doesn’t release adequate amounts of ACTH, or the adrenal glands fail to release their hormones in response to ACTH. The medical term for Addison’s disease is hypoadrenocorticism.